Artificial Intelligence Operations & Data Science Services Publications

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Selected examples of publications that resulted from collaborations with the Informatics Core.   

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ChatGPT for digital pathology research

M Omar, V Ullanat, M Loda, L Marchionni, R Umeton

The Lancet Digital Health, 2024

GPT-4 in a Cancer Center — Institute-Wide Deployment Challenges and Lessons Learned

R Umeton, A Kwok, R Maurya, D Leco, N Lenane, J Willcox, GA Abel, M Tolikas, Dana-Farber Generative AI Governance Committee, JM Johnson

NEJM AI, 1, 4, 2024

Genomic and immunophenotypic landscape of acquired resistance to PD-(L) 1 blockade in non-small-cell lung cancer

B Ricciuti, G Lamberti, SR Puchala, NR Mahadevan, JR Lin, JV Alessi, A Chowdhury, et al.

Journal of Clinical Oncology, JCO.23.00580, 2024

Federated benchmarking of medical artificial intelligence with MedPerf

A Karargyris, R Umeton, MJ Sheller, A Aristizabal, J George, A Wuest, et al.

Nature Machine Intelligence, 5, 799, 2023

A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories

D Placido, B Yuan, JX Hjaltelin, C Zheng, AD Haue, PJ Chmura, C Yuan, et al.

Nature Medicine, 29, 1113, 2023

GaNDLF: the generally nuanced deep learning framework for scalable end-to-end clinical workflows

S Pati, SP Thakur, İE Hamamcı, U Baid, B Baheti, M Bhalerao, O Güley, et al.

Communications Engineering, 2 (1), 23, 2023

Measuring Palliative Care Communication via Telehealth: A Pilot Study

EC Tarbi, BN Durieux, JM Brain, A Kwok, R Umeton, S Samineni, et al.

Journal of Pain and Symptom Management, 2023

Genomic and immunophenotypic landscape of acquired resistance to PD-(L) 1 blockade in non-small cell lung cancer

B Ricciuti, G Lamberti, S Puchala, N Mahadevan, J Alessi, X Wang, Y Li, et al.

Cancer Research, 83, 6629, 2023

PI‐RADS 3 score: A retrospective experience of clinically significant prostate cancer detection

A Camacho, F Salah, CP Bay, J Waring, R Umeton, MS Hirsch, AP Cole, et al.

BJUI Compass, 2023

Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states

J Nyman, T Denize, Z Bakouny, C Labaki, BM Titchen, K Bi, SN Hari, et al.

bioRxiv, 2023.01. 18.524545, 2023

Book Chapter - A Review of Medical Federated Learning: Applications in Oncology and Cancer Research

A Chowdhury, H Kassem, N Padoy, R Umeton, A Karargyris

Book Chapter MICCAI - Springer 1 (dx.doi.org/10.6084/m9.figshare.21071200), 3-24, 2022

Association of High Tumor Mutation Burden in Non–Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 …

B Ricciuti, X Wang, JV Alessi, H Rizvi, NR Mahadevan, YY Li, A Polio, ...

JAMA Oncology, doi:10.1001/jamaoncol.2022.1981, 2022

A multi-omics signature for patients’ risk classification in prostate cancer

Z Xu, E Benedetti, R Carelli, J Rosenthal, H Pakula, M Omar, R Umeton, ...

Cancer Research, 82 (12), 5858, 2022

Associations Between Family Member Involvement and Outcomes of Patients Admitted to the Intensive Care Unit: Retrospective Cohort Study

TF Gray, A Kwok, KM Do, S Zeng, ET Moseley, YM Dbeis, R Umeton, ...

JMIR medical informatics 10 (6), e33921, 2022

Using attention-based deep multiple instance learning to identify key genetic alterations in prostate cancer from whole slide images

M Omar, Z Xu, R Carelli, J Rosenthal, D Brundage, DC Salles, EL Imada, ...

Cancer Research 82 (12), 462, 2022

AI predicts risk of pancreatic cancer from disease trajectories using real-world electronic health records (EHRs) from Denmark and the USA

D Placido, B Yuan, JX Hjaltelin, AD Haue, PJ Chmura, C Yuan, J Kim, ...

Cancer Research 82 (12), LB550, 2022

Deep learning for cancer symptoms monitoring on the basis of electronic health record unstructured clinical notes

C Lindvall, CY Deng, ND Agaronnik, A Kwok, S Samineni, R Umeton, ...

JCO Clinical Cancer Informatics 6, e2100136, 2022

Building tools for machine learning and artificial intelligence in cancer research: best practices and a case study with the PathML toolkit for computational pathology

J Rosenthal, R Carelli, M Omar, D Brundage, E Halbert, J Nyman, SN Hari, ...

Molecular Cancer Research 21 (655), 2022

Multi-omics biomarkers aid prostate cancer prognostication

Z Xu, M Omar, E Benedetti, J Rosenthal, R Umeton, J Krumsiek, ...

bioRxiv, 2022

Book - Machine Learning, Optimization, and Data Science: 7th International Conference, LOD 2021, Grasmere, UK, October 4-8, 2021, Revised Selected Papers, Part I

G Nicosia, V Ojha, E La Malfa, G La Malfa, G Jansen, PM Pardalos, ...

Book - Springer 13163 (http://doi.org/10.1007/978-3-030-95467-3), 1-644, 2022

Book - Machine Learning, Optimization, and Data Science: 7th International Conference, LOD 2021, Grasmere, UK, October 4-8, 2021, Revised Selected Papers, Part II

G Nicosia, V Ojha, E La Malfa, G La Malfa, G Jansen, PM Pardalos, ...

Book - Springer 13164 (http://doi.org/10.1007/978-3-030-95470-3), 1-548, 2022

Identification and Management of Pathogenic Variants in BRCA1, BRCA2, and PALB2 in a Tumor-Only Genomic Testing Program

BL Bychkovsky, T Li, J Sotelo, N Tayob, J Mercado, I Gomy, A Chittenden, ...

Clinical Cancer Research: an official journal of the American Association …, 2022

Whole Slide Image to DICOM Conversion as Event-Driven Cloud Infrastructure

D Brundage, J Rosenthal, R Carelli, S Rand, R Umeton, M Loda, ...

arXiv preprint arXiv:2203.13888, 2022

MedPerf: Open Benchmarking Platform for Medical Artificial Intelligence using Federated Evaluation

A Karargyris, R Umeton, MJ Sheller, A Aristizabal, J George, S Bala, ...

arXiv preprint arXiv:2110.01406, 2021

Applying Self-Supervised Learning to Medicine: Review of the State of the Art and Medical Implementations

A Chowdhury, J Rosenthal, J Waring, R Umeton

Informatics 8 (3, Machine Learning in Healthcare), 59, 2021

Pancreatic cancer risk predicted from disease trajectories using deep learning

D Placido, B Yuan, JX Hu, AD Haue, C Yuan, J Kim, R Umeton, G Antell, ...

bioRxiv, 2021

Metabolomics of Prostate Cancer Gleason Score in Tumor Tissue and Serum

KL Penney, S Tyekucheva, J Rosenthal, H El Fandy, R Carelli, ...

Molecular Cancer Research [machine learning; metabolomics; prostate cancer …, 2021