Current research projects of the Patient Reported Data Program include:
Oral Cancer Directed Therapy (OCDT)
The OCDT-focused intervention expands ePRO collection beyond clinic visits to between clinic visits. Adult patients with breast or gastrointestinal cancer who are taking any one of eight oral chemotherapy drugs are eligible to participate. In some patients, OCDT, as an alternative to IV chemotherapy, may reduce therapy adherence and delay real-time identification of toxicities, leading to an increase in unplanned urgent visits, reduced treatment efficacy, and more mortality overall. The study’s aims are to:
- Develop a tool to expand the frequency of ePRO collection beyond clinic visits
- Assess the feasibility and patient/clinician acceptance of the tool
- Assess toxicity of treatment at home
- Evaluate treatment adherence
- Integrate toxicity and adherence reporting into clinical practice
Funded by:
2019 MSCO Quality and Innovation Grant Award
Donaghue Foundation
REACH: Resilience and Equity in Aging, Cancer, and Health
REACH aims to expand cancer care treatment to include a geriatric consult for older adults (age 70 or older) with a gastrointestinal cancer who could benefit from a geriatric consult, as determined by a fitness assessment. The study’s objectives are to:
Increase efficacy of care for older adults
Address the specific needs of older adults in cancer care
Funded by:
DFCI institutional funding
Recent publications
Ivatury SJ, Hazard-Jenkins HW, Brooks GA, McCleary NJ, Wong SL, Schrag D. Translation of patient-reported outcomes in oncology clinical trials to everyday practice. Annals of Surgical Oncology, 2020 Jan;27(1):65-72.
Recent presentations
Patient-reported outcomes and emergency department (ED) visits among gastrointestinal (GI) cancer patients prescribed anti-CTLA4/PD-1/L-1 antibody immunotherapy (AACR, 2020)
Leveraging the Electronic Health Record for patient-facing Lynch syndrome risk assessment in oncology (AcademyHealth ARM, 2020)
Defining best implementation strategies for electronic patient reported outcomes (ePRO) in ambulatory oncology practice: Validation of source data for audit and feedback (AcademyHealth D&I, 2020)
Impact of systematic electronic patient reported outcomes on oral cancer-directed therapy toxicity and adherence (AMIA, 2020)
Patient reported risk stratification for Lynch Syndrome in oncology: PREMM5 build and integration in Electronic Health Record (AMIA, 2020)
Patient-reported health literacy and numeracy among new patients seeking consultation at a comprehensive cancer center (ASCO, 2020, AcademyHealth ARM, 2020)
Distribution and frequency of patient-reported symptomatic adverse events at a comprehensive cancer center (ASCO, 2020)
Translating Evidence into Practice: Patient Reported Outcomes in Ambulatory Oncology Practice (NCCN, 2020/2021)